December 2011
Interim Report of Zone-16 WPA Funded Project: Prevalence of Common mental disorders in subjects with diabetes mellitus

This study was to be conducted at two sites - India and Sri Lanka. At the Indian site 250 patients were to be recruited and an equal number of patients were to be recruited at the Sri Lankan site. However, to best of our knowledge the site at Srilanka is not yet operational. We wrote a number of times to Dr E Mohan Das, zone 16 representative to request the identified investigators at Sri Lankan site to coordinate with us, but till date we have not been contacted.

Indian Site: Post Graduate Institute of Medical Education and Research, Chandigarh, India -160012 

Investigators from the Indian Site
Ajit Avasthi
(Principal Investigator), Professor, Department of Psychiatry, PGIMER, Chandigarh 

Sandeep Grover (Co-Principal Investigator), Assistant Professor, Department of Psychiatry, PGIMER, Chandigarh 

Anil Bhansali (Co-Principal Investigator), Professor, Department of Endocrinology, PGIMER, Chandigarh 

Aims and Objectives of the Study
To study the prevalence of common mental disorders in subjects with diabetes mellitus. 


Site: Post Graduate Institute of Medical Education and Research, Chandigarh, India
Sample size:
250 subjects  

Inclusion Criteria 

1. Patients with established T2DM as defined by American Diabetes Association (ADA 1997) criteria 

2. Patients able to read Hindi 

Exclusion Criteria 

1. Patients who were too sick to participate. 

2. Patients who were unable to read Hindi. 


Socio-demographic profile sheet: A proforma was designed for the study to record the relevant sociodemographic data. 

Clinical profile sheet: A proforma was designed for this study to record the following clinical details: duration of diabetes mellitus, complications, anthropometry, past psychiatric history, past psychiatric treatment, family history of psychiatric disorders, etc. 

Patient Health Questionnaire (PHQ): It is a standardized, brief and easy diagnostic assessment procedure designed for the busy clinician. According to the length of the questionnaire, PHQ has three versions: 2-page version (Brief PHQ) that covers only mood and panic disorder; 3-page version which covers 8 diagnoses; and the 4-page version, which in addition to the above has questions about menstruation, pregnancy, child birth, and recent psychosocial stressors. For this study, the 3-page version was used to screen as it covers the common mental disorders.

The 3-page questionnaire has questions about symptoms and signs divided into eight diagnostic categories corresponding to specific DSM-IV diagnoses. These are threshold disorders corresponding to major depressive disorder, panic disorder, other anxiety disorder, bulimia nervosa and sub-threshold disorders (in which the criteria for disorders encompass fewer symptoms than are required for any specific DSM-IV diagnosis) such as other depressive disorders, probable alcohol abuse or dependence, somatoform and binge eating disorders. There is an additional item asking about the patient’s functional status in relation to the symptoms.

Patient’s responses to the PHQ indicate to the physician, which if any, of the diagnostic categories is applicable to the patient. The evaluation by the physician can be done at any time during the encounter with the patient, but after the reasons for the patient’s visit are addressed to after evaluating each patient but before reviewing the PHQ, the physician notes whether the patient is new or established, types of current physical disorders and the physician’s opinion about any current mental disorder in the patient. The clinician then scans the completed questionnaire, verifies positive responses and applies diagnostic algorithms that are abbreviated at the bottom of each page. Before making a final diagnosis, a physician rules out any physical cause for the psychiatric disorders. Further, before diagnosing a subject as suffering from depressive disorder, the physician should evaluate the patient for the history of mania and normal bereavement10.

For the study, Hindi translation of 3-page questionnaire was used. This translation was done for one of the previous studies from our centre using standardized methodology for translation.    


All the patients with T2DM attending the Endocrinology Outpatient Clinic in Nehru Hospital, PGIMER were initially asked to fill the Hindi version of the PHQ. Informed and written consent was obtained from all the participants. Those found to fulfill any common mental disorder on PHQ were assessed further by a qualified psychiatrist, who interviewed the patients using a semi-structured interview to ascertain the psychiatric diagnosis. Subjects found to have psychiatric disorders were offered treatment. The socio-demographic and clinical data will be recorded in a systematic fashion.


Till date 184 patients have been recruited.

Sociodemographics is shown in table-1.

Table-1: Sociodemographic variables


Mean (SD) / Frequency (%)

Age in years

50.76 (9.7)

Education in years

10.05 (5.01)



88 (47.8)
96 (52.2)

Marital Status

Currently married

170 (92.4)
14 (7.6)


Onpaid employment

66 (35.9)
118 (64.1)

Family Type


96 (52.2)
88 (47.8)



139 (75.5)
45 (24.5)


Table-2: Clinical Profile and Psychiatric morbidity


Mean (SD) / Frequency (%)

Duration of the illness in months

86.82 (77.29)

Diagnosis with PHQ


95 (51.6)
89 (48.4)

Diagnosis by the psychiatrist


81 (44)
103 (56)


Table-2: Clinical Profile and Psychiatric morbidity




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